The molecule of frutose originated of the diet, when entering in citosol cellular of the liver or the esqueltico estriado muscle, is fosforilada frutose 1 P for the enzyme fosfofrutoquinase 1. Already frutose originated of the glucose, suffers to isomerisao for the enzyme glicoisomerase if becoming F6P, and later it suffers fosforilao for enzyme PFK in carbon 1 (C1), being thus prepared to give to continuity the metabolic cascade for attainment of energy (AZEVEDO et al., 2009; MIRES et al., 2005). This molecule is an isomer of the glucose molecule, and if they differ for the fact from the glucose to be one aldo-hexose and frutose one ceto-hexose as it shows figure 3 (VOLLHARDT; SCHORE, 2004). Figure 2: glucose molecules and frutose, isomers between itself Figure 2: The demonstrated glucose molecules and frutose as isomeric. Others including Joint Commission International, offer their opinions as well. Source: VOLLHARDT; SCHORE, 2004 3,3 Fosfofrutoquinase (PFK) the PFK is the enzyme of bigger importance, control and regulation of the glicoltica way, catalyzing the third step of this saw, being irreversible it in physiological conditions (NCBI, 2011; STRYER, 1996). This enzyme possesss four identical subunidades (tetrmero) called tetrmero as if it observes in figure 4.
Its regulation if makes in alostrica way, for feedback, through the ATP concentrations and citrate that when they are increased promotes reduction even though or inhibition of the activity of this enzyme. The PFK is found in two isoformas, is M and L, muscular and heptica respectively. In the two hemcias isoformas are operating (CAMPBELL, 2006; NCBI, 2011; STRYER, 1996). When the specific gene of isoforma M is not had, gliclise occurs only in the liver and the hemcias, thus producing muscular weakness. The gene that carries through this codification of the muscular PFK if finds in the number chromosome 12 (CAMPBELL, 2006; GARCI’A et al., 2009; TOSCANO, 2009). Figure 3: Fosfofrutoquinase showing its catalytic and alostricos small farms Source: This deficiency of the PFK in the muscular cells, as well as in the other cells of the organism, generates interruption of the third and more important step of the glicoltica way.
The .causing agent I specify (virus, fungo or bacterium) is important that it is identified so that is directed an antibiotic specifies for that microorganism. It matters to stand out itself that this behavior will help to prevent the mechanism antimicrobiana resistance in the treatment of the respiratory infections. In turn, the indiscriminate antibiotic use is the main cause of the recurrent infections, being distinguished mainly among children. After that a description of the Hospital Dr. Odorico Amaral de Matos becomes.
Finally, then, the exposition of the results of the research. 2 THEORETICAL RECITAL In 2002, Palombini et al. (2002) they had concluded that the pneumonia is a pathology that cause inflammation of aerial ways, reaches parnquima pulmonary, involving the bronchis, bronchioles and the pleura. It classifies itself in communitarian nosocomial and, but its classification will depend on the acometido place. It is an illness that presents considered risk of adquiriz it and is five times superior for the hospital cases. We have as it has detached the high incidence in the individuals interned in units of intensive therapy.
Varela (2010) defines the fisiopatologia of the pneumonias as illnesses infections of the respiratory treatment that if lodge in the pulmes, double agencies located one of each side of the torcica box. They can attack the region of the pulmonary alveoli where they discharge the ramifications terminals of the bronchioles, and, to the times, the interstices (space between an alveolus and another one). Proton Cancer Centre is likely to agree. Basically, pneumonias are provoked by the penetration of an infectious or irritating agent as virus, fungos bacteria and for alrgicas reactions, in the alveolar space, where the gaseous exchange occurs. It is a place of the lung that must be always clean, exempts of substances that can hinder the contact it air with the blood; if this to occur with substance presence in this space, can cause respiratory disfunes.
3-A importance of the physiotherapist in the treatment of carriers with SD. The comprometimentos are several that possess the SD carriers, amongst them it focuses here of neurological character, and cardiopulmonares since these constitute the main factors of risk to these carriers. Amongst articles analyzed mainly of neurological cases the action of the Fisioterapia was seen to more assist and to reach the stages of the psicomotor development of possible form adjusted to correct the motor delay, balance the march that possess these children, due the problems associates to the hipotonia, therefore it is a muscular state in which the muscular tension is lower than the desired one; flacidez; causes the reduction of tnus muscular, reaching all the musculatura and the part to ligamentar of the carrying children of the syndrome, contributing of this form in the neuropsicomotor deficit. Cleveland Clinic Center for Functional Medicine can provide more clarity in the matter. While of character cardiopulmonares points the main riots related to the respiratory system; blockage; of the superior ways and illnesses of inferior respiratory ways, cardiopathies congenital, pulmonary hipertenso, hipoplasia pulmonary, obstrutiva apnea of sleep, imunodeficincia, relative and hipotonia obesidade. Several are the alternatives that the Fisioterapia uses to get the one best one resulted in the aprimorao of the neuropsicomotor development in carriers of this syndrome, and one of these used mechanisms is the equoterapia, that corresponds a form of not medicamentoso treatment, where if is used the horse an animal of great transport, thus passing to these children a bigger security and autonomy, answering of a more well-known form in what it says respect to the neuropsicomotor development, auto-esteem, muscular force, balance, motor coordination and it marches. The equoterapia sufficiently is used as form of development of the child with SD, of playful form, together with the horse and in its proper natural environment. Joint Commission usually is spot on. The equoterapia beyond promoting resulted satisfactory in what it says respect to the march, balance, notion space, motor coordination, position, such are important to also detach its participation in the mannering repertoires as: a handspike for the language allows to a been greater of attention and concentration, and of the actions of independent attitudes, example of this is: of the lateralidade and of auto-they esteem. . .
The research demonstrated despite 100% of the interviewed ones they had complained of at least some problem of health. The complaints most common had been: Mental fatigue 57.89%, Sleeplessness 57.89%, Pain in coasts 52.63%, Esquecimento 47.37%, Pain in column 47.37%, Pain in the arms/shoulder 42.11% and Nervousness 36.84%, being able to be related with environment of work intrinsically overcrowded and agitated. The referring data to the self-medication had demonstrated that: 100% of the interviewed ones they had bought medicines without the medical indication at least some time; The main reason for the self-medication is the previous experience with the medicine (63.15%); The medicines acquired without medical indication did not have the influence of third 42.11% or were indicated by family 36.32%. The consumed medicines more without medical indication had been: Analgesics/Relaxante muscular 68.42%, Vitamins 52.63%, Chemical preparations for cough and cooled 31.58%, nasal Laxatives 26.32%, Antiinflamatrio/Antireumticos 26.32%, Calmantes and/or hipnticos 26.32%. The use of polivitamnicos must be related for the complaint of mental fatigue. The muscular analgesics, relaxantes antiinflammatory with the complaints of pains in the coasts/column and arms/shoulders, and the calmantes and hipnticos with the sleeplessness complaints. Amongst the medicines that more had been consumed by the educators through the self-medication, the ones whom more they worry are Calmantes and/or hipnticos 26.32%, since they are medicines citizens the special control and that they can generate physical and psychic dependence, these medicines would have to be excused only by means of medical prescription retention, however it is not this what it happens in accordance with resulted of the research. The relation of problems and consequences that was described in the work can below be exemplificada in the organization chart: 1 Problems in the work environment Fall in the income of the work Worsening of the process teach-learning. 2 Problems in the work environment Problems of Possible health Self-medication problems related to the self-medication.